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Alternative to Anti-VEGF Shows Safety, Efficacy in Diabetic Macular Edema
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115290.jpg"/> (MedPage Today) -- A single intravitreal injection of UBX1325 (foselutoclax), a novel senolytic small molecule inhibitor, had a tolerable safety profile and "trends suggestive of potential efficacy" in patients with diabetic macular edema (DME...


Young-Onset Dementia Risk Rises With Metabolic Syndrome
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115253.jpg"/> (MedPage Today) -- The risk of young-onset dementia -- dementia before age 65 -- was higher in people with metabolic syndrome, a nationwide population-based study in Korea showed. Across nearly 2 million people with a mean age of 49, metabolic...


Lorundrostat Lowered BP in Uncontrolled, Treatment-Resistant Hypertension
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115252.jpg"/> (MedPage Today) -- Lorundrostat reduced blood pressure (BP) in people with confirmed uncontrolled and treatment-resistant hypertension, according to a double-blind randomized trial. With background antihypertensive medication provided to participants...


The Truth About Electrolytes, According to a Nephrologist
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115231.jpg"/> (MedPage Today) -- Welcome to Culture Clinic, MedPage Today's collaboration with Northwell Health to offer a healthcare professional's take on the latest viral medical topics. In an aisle where sports drinks like Gatorade once reigned supreme...


Medicaid Often Restricts Access to Heart-Protective Diabetes Agents
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115216.jpg"/> (MedPage Today) -- Medicaid plans often put up barriers around newer classes of diabetes medications that offer cardioprotection, according to a national study of formulary policies as of March 2024. Mainly driven by restrictive formulary policies...


Common Intervention Lowers Dementia Risk, Trial Shows
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115214.jpg"/> (MedPage Today) -- Reducing hypertension dropped dementia risk by 15% in the open-label China Rural Hypertension Control phase III (CRHC-3) trial of nearly 34,000 people. At 48 months, all-cause dementia among people with high blood pressure was...


Intracerebral Hemorrhage: Strict BP Control Not to Blame for Pinprick Brain Lesions
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115210.jpg"/> (MedPage Today) -- The acute intensive blood pressure (BP) lowering recommended after intracerebral hemorrhage (ICH) did not increase small-volume infarcts compared with looser control in a small randomized trial. Of 79 patients in the ICHADAPT...


Hearing Loss and Heart Failure; Improved TAVR Outcomes
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115190.jpg"/> (MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center...


Diabetes, Heart Disease Drugs Recalled; New Trump Order; Maple Syrup's Health Claims
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115144.jpg"/> (MedPage Today) -- Note that some links may require registration or subscription. MedPage Today is collecting stories of HHS staffers across all agencies affected by Trump administration cuts. If you want to share your story, please email MPT_Editorial...


NKF Roundup: Phosphate Binder Barriers, OTC Pills and Stones, Bad Itching, and More
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115142.jpg"/> (MedPage Today) -- BOSTON -- Some of the latest studies in the field of nephrology presented at the National Kidney Foundation Spring Clinical Meeting focused on the impact of heat on kidney transplant outcomes, the risk of kidney stones with...


Read the Results of Trump's 2025 Physical Exam
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115125.jpg"/> (MedPage Today) -- On April 11, 2025, President Donald J. Trump underwent his annual physical examination at Walter Reed National Military Medical Center. I performed and supervised the comprehensive exam, which included diagnostic and laboratory...


Vaccine Advisors to Meet; Donated Organs Left Unused; Counterfeit Ozempic Warning
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115123.jpg"/> (MedPage Today) -- Note that some links may require registration or subscription. MedPage Today is collecting stories of HHS staffers across all agencies affected by Trump administration cuts. If you want to share your story, please email MPT_Editorial...


Study Pinpoints Barriers to Kids Receiving Living-Donor Kidney Transplants
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115118.jpg"/> (MedPage Today) -- BOSTON -- Several factors may decrease a child's chances of receiving a living-donor kidney transplant, a mixed-methods study found. In a review of 93 pediatric kidney transplants, the following patient characteristics were...


Faster, More Frequent Proteinuria Reduction With Sparsentan in FSGS
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115109.jpg"/> (MedPage Today) -- BOSTON -- Patients with focal segmental glomerulosclerosis (FSGS) achieved some degree of proteinuria remission more often and more quickly on sparsentan (Filspari) than irbesartan (Avapro), secondary analyses of the phase...


Estimated GFR Equation Matters When Dosing Chemotherapy in Cancer Patients
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115097.jpg"/> (MedPage Today) -- BOSTON -- Some equations used to calculate estimated glomerular filtration rate (eGFR) may alter chemotherapy dosing in cancer patients, a prospective study indicated. Nearly 300 adults beginning treatment for cancer had their...


Doctors Remove Pig Kidney From Alabama Woman After a Record 130 Days
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115088.jpg"/> (MedPage Today) -- An Alabama woman who lived with a pig kidney for a record 130 days had the organ removed after her body began rejecting it and is back on dialysis, doctors announced Friday -- a disappointment in the ongoing quest for animal...


Renal Outcomes Seem to Differ by Gender After Living Kidney Donation
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115095.jpg"/> (MedPage Today) -- BOSTON -- After living kidney donation, projection of renal function may vary by gender, a retrospective cohort study of 174,311 living kidney donors suggested. Over a median 6.7 months, the incidence rate of worsening post...


Healthy Aging and Diet; Global Effect of Cardiovascular Risk Factors
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115087.jpg"/> (MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center...


Retrospective Study Links COVID in Kids With Post-Acute Kidney Outcomes
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115093.jpg"/> (MedPage Today) -- COVID-19 infection in children and adolescents was tied to a higher risk of adverse post-acute kidney outcomes, especially among those with preexisting chronic kidney disease (CKD) or acute kidney injury (AKI), retrospective...


One Diuretic May Be Better for Hypertensive Patients With Kidney Stone History
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115091.jpg"/> (MedPage Today) -- BOSTON -- In people with hypertension, a history of kidney stones may inform the choice of diuretic for stone prevention, according to a secondary analysis of the Diuretic Comparison Project. Among 1,164 older veterans with...


Soaring Temps Spell Trouble for Kidney Transplant Recipients
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115080.jpg"/> (MedPage Today) -- BOSTON -- Exposure to high temperatures may be renally taxing for kidney transplant recipients, a researcher reported here. Among nearly 64,000 recipients from 250 transplant centers around the U.S., every additional year...